Bone density and long-term anticonvulsant therapy.
نویسندگان
چکیده
منابع مشابه
Bone density of ambulatory adult patients receiving long-term anticonvulsant drug therapy.
BACKGROUND Chronic antiepileptic therapy has been associated with metabolic bone diseases including osteomalacia and osteoporosis. The object of this study was to assess the effect of first line anticonvulsants on bone density and vitamin D levels in Iranian ambulatory patients. METHODS We conducted a cross-sectional study assessing bone density with dual energy X-ray absorptiometry at the hi...
متن کاملMandibular bone density and calcium content affected by long-term anticonvulsant treatment in rats.
OBJECTIVE Bone is perpetually absorbed and reformed, serving also to electrolyte homeostasis, mainly for calcium and phosphorus. Anticonvulsant medications are traditionally considered harmful to bone because of their interaction with the metabolism of vitamin D, due to hepatic enzyme induction. A study of the effect of anticonvulsant medications on mandibular bone quality was undertaken. MAT...
متن کاملBone mineral density, vitamin D and anticonvulsant therapy.
UNLABELLED The aim of this study was to assess bone mineral density and vitamin D metabolism in patients on chronic anticonvulsant therapy. METHODS Sixty-nine men, outpatients on chronic anticonvulsant therapy, who had been treated for at least 5 years, were studied, comparing them to thirty healthy controls. Bone mineral density was measured as well as serum levels of calcium, ionized calciu...
متن کاملEffect of Long-Term Captopril Administration on Bone Density and Orthodontic Tooth Movement
Background and Aim: Captopril is an oral angiotensin-converting-enzyme (ACE) inhibitor extensively used in the treatment of hypertension and heart failure. ACE has been suggested to function in bone cells and might therefore impact orthodontic tooth movement (OTM). Considering the controversy surrounding the effects of ACE and its inhibitors on osseous tissues, we aimed to evaluate the effect o...
متن کاملMacrocytosis in Down's syndrome and during long-term anticonvulsant therapy.
In a group of non-anaemic mentally retarded patients a significant increase in mean red cell volume has been demonstrated in epileptic patients being treated with anticonvulsants. The possible sites of interference of anticonvulsants with folate activity in the body, and problems associated with folic acid supplements during anticonvulsant therapy, are discussed. During the survey it was confir...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5771.433-a